White Lady centers on Pearl (Pauleen Luna), a simple and smart girl who just arrived in the city to attend college. For reasons she cannot explain and understand, Pearl is haunted by the ghost of a white lady said to be frequenting the school grounds. Determined to solve the mystery, Pearl decides to investigate and hears about the story of Christina (Angelica Panganiban), a simple girl driven into hiding by a clique of students who get by through bullying others. Later on, Pearl discovers a deadly and horrifying secret that connects her, her schoolmates and the white lady that terrorizes their school.